Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823481 | 0.85 | KMT2A (0.63) | PLA2G2AKMT2ALMNAGAAMAPT | |
| SCHEMBL3854526 | 0.85 | PLA2G2A (0.59) | PLA2G2AKMT2ALMNAALDH1A1TSHR | |
| SCHEMBL3855495 | 0.82 | PLA2G2A (0.65) | PLA2G2AKMT2ALMNAALDH1A1TSHR | |
| SCHEMBL6920117 | 0.82 | CA12 (0.48) | PLA2G2AKMT2ALMNAGAAMAPT | |
| SCHEMBL31222301 | 0.81 | CYP19A1 (0.60) | PLA2G2AKMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL2244878 | 0.81 | CYP19A1 (0.60) | PLA2G2AKMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL6820689 | 0.81 | PLA2G2A (0.68) | PLA2G2AKMT2ALMNAMAPTPKM | |
| SCHEMBL2246814 | 0.77 | CYP19A1 (0.70) | PLA2G2AKMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL3855156 | 0.76 | GRIK2 (0.50) | PLA2G2AKMT2ALMNAGAAALDH1A1 | |
| SCHEMBL17969632 | 0.76 | NPC1 (0.51) | PLA2G2AKMT2ALMNACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |