Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 8/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 3/20 | 0.44 |
| ▸ | CA5A | P35218 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2226182 | 0.84 | CA2 (0.56) | PTGES2CA2CA1CA9CA12 | |
| SCHEMBL9492408 | 0.82 | CA2 (0.55) | PTGES2CA2CA1CA9CA12 | |
| SCHEMBL1080972 | 0.82 | CA2 (0.61) | CA2CA1CA9CA12CA14 | |
| SCHEMBL8347239 | 0.80 | CA2 (0.58) | CA2CA1CA9CA12CA14 | |
| SCHEMBL31087243 | 0.77 | KDM4E (0.52) | MAP2K7CDC25ACDC25BALDH1A1SMN1; SMN2 | |
| SCHEMBL5890646 | 0.77 | KDM4E (0.52) | MAP2K7CDC25ACDC25BALDH1A1SMN1; SMN2 | |
| SCHEMBL6820364 | 0.76 | CA2 (0.50) | CA2CA1CA9CA12CA14 | |
| SCHEMBL9819445 | 0.76 | CA2 (0.47) | PTGES2CA2CA1CA9CA12 | |
| SCHEMBL5491594 | 0.75 | PTGES2 (0.48) | PTGES2CA2CA1CA9CA12 | |
| SCHEMBL1116406 | 0.75 | CA2 (0.56) | CA2CA1CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043917-A1 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |