Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160654 | 0.86 | MAPT (0.51) | KMT2AMEN1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL5160644 | 0.86 | MAPT (0.51) | KMT2AMEN1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL2234342 | 0.86 | PTPRB (0.52) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL5019060 | 0.84 | KMT2A (0.52) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL22338893 | 0.84 | KMT2A (0.52) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL3317059 | 0.83 | ALDH1A1 (0.62) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL4367409 | 0.83 | ALDH1A1 (0.62) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL240405 | 0.83 | ALDH1A1 (0.62) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL4592273 | 0.82 | MAPK1 (0.50) | KMT2AMEN1LMNANPC1RAB9A | |
| SCHEMBL19369766 | 0.82 | MAPK1 (0.50) | KMT2AMEN1LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087656-A1 | CONJUGATES OF 2,4-ETHANO-BRIDGED AND 2,4-PROPANO-BRIDGED 3,6,9-TRIAZA-NONANOIC ACID, 3N,6N,9,9N-TETRAETHANOIC ACID, AND CORRESPONDING PHOSPHORIC ACID METHYLENE DERIVATIVES AND THE SUBSTITUTION PRODUCTS THEREOF WITH BIOMOLECULES, METHODS FOR THE PRODUCTION THEREOF, AND THE USE OF THE SAME FOR PRODU | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-10-14 | — | — | WO | disclosed |
| US-5225431-A | Treatment of migraine | BURROUGHS WELLCOME CO. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0313397-B1 | THERAPEUTIC HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| EP-0313397-A1 | Therapeutic heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-04-26 | — | — | EP | disclosed |