SCHEMBL240405

SCHEMBL240405

COC(=O)[C@@H](N)Cc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.62
MMP2 P08253 2/20 0.50
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
LMNA P02545 1/20 0.48
DPP4 P27487 2/20 0.46
DPP7 Q9UHL4 2/20 0.46
DPP8 Q6V1X1 1/20 0.46
DPP9 Q86TI2 1/20 0.46
IDO1 P14902 2/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
NPC1 O15118 2/20 0.46
TP53 P04637 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAOB P27338 1/20 0.46
MC4R P32245 1/20 0.46
GAA P10253 1/20 0.45
MAPK1 P28482 1/20 0.45
FAP Q12884 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3317059 1.00 ALDH1A1 (0.62) ALDH1A1MMP2MEN1KMT2ALMNA
SCHEMBL4367409 1.00 ALDH1A1 (0.62) ALDH1A1MMP2MEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL4371678 0.98 ALDH1A1 (0.64) ALDH1A1MMP2MEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL1230535 0.98 ALDH1A1 (0.64) ALDH1A1MMP2MEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL240404 0.98 ALDH1A1 (0.64) ALDH1A1MMP2MEN1KMT2ALMNA
SCHEMBL27546222 0.98 ALDH1A1 (0.61) ALDH1A1MMP2MEN1KMT2ALMNA
SCHEMBL8211198 0.93 ALDH1A1 (0.56) ALDH1A1MMP2MEN1KMT2ADPP4
SCHEMBL4097192 0.93 ALDH1A1 (0.56) ALDH1A1MMP2MEN1KMT2ADPP4
SCHEMBL11651148 0.88 MMP2 (0.49) ALDH1A1MMP2LMNADPP4DPP7
SCHEMBL1859542 0.87 MAPT (0.50) ALDH1A1MMP2LMNADPP4DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 426 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119193761-A Test paper and method for semi-quantitatively detecting leucine aminopeptidase 广州达安基因股份有限公司 2024-12-27 CN claimed
EP-0843673-B1 ONE POT SYNTHESIS OF 2-OXAZOLIDINONE DERIVATIVES ASTRAZENECA AB (SE) 2001-11-07 EP claimed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 US disclosed
EP-3303367-B1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2025-06-18 EP disclosed
CN-119193761-A Test paper and method for semi-quantitatively detecting leucine aminopeptidase 广州达安基因股份有限公司 2024-12-27 CN disclosed
CN-119193761-A Test paper and method for semi-quantitatively detecting leucine aminopeptidase 广州达安基因股份有限公司 2024-12-27 CN disclosed
CN-118344557-A Diketopiperazine-based polyurethane elastomer and preparation method and application thereof 天津科技大学 2024-07-16 CN disclosed
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME UNIV NEW YORK (US) 2024-06-13 US disclosed
US-20240124539-A1 CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME NEW YORK UNIVERSITY 2024-04-18 US disclosed
US-11891422-B2 NEMO coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2024-02-06 US disclosed
US-5099069-A Radioactive materials for diagnosis and treatment of tumors and cancer by joining monoclonal antibodies GANSOW OTTO A (US) 1992-03-24 US disclosed
US-4837305-A Derivatives of β-adrenergic antagonists THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1989-06-06 US disclosed
US-4831175-A Backbone polysubstituted chelates for forming a metal chelate-protein conjugate THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1989-05-16 US disclosed
EP-0117089-B1 BETA-ADRENERGIC ANTAGONIST COMPOUNDS AND DERIVATIVES OF BETA-ADRENERGIC ANTAGONISTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1988-12-14 EP disclosed
US-4687873-A Derivatives of β-adrenergic antagonists THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1987-08-18 US disclosed
US-4622420-A Chelating agents and method THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1986-11-11 US disclosed
US-4587046-A Drug-carrier conjugates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1986-05-06 US disclosed
EP-0117089-A1 Beta-adrenergic antagonist compounds and derivatives of beta-adrenergic antagonists THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1984-08-29 EP disclosed
EP-0094844-A2 Drug-carrier conjugates THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1983-11-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH ALDH1A1 3890/4885MMP2 4776/4885MEN1 200/4885
US-20240124539-A1 CROSSLINKED HELIX DIMER MIMICS OF SOS AND METHODS OF USING SAME SOS2, SOS1, F2 ALDH1A1 3199/4885MMP2 4631/4885MEN1 452/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 ALDH1A1 4748/4885MMP2 4688/4885MEN1 2283/4885
US-11891422-B2 NEMO coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH ALDH1A1 3890/4885MMP2 4776/4885MEN1 200/4885
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH ALDH1A1 3702/4885MMP2 4799/4885MEN1 144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.