Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26299057 | 0.81 | ALDH1A1 (0.50) | LMNANAPRTP4HTML3MBTL1ALDH1A1 | |
| SCHEMBL3320709 | 0.79 | GSK3B (0.58) | POLBLMNANAPRTP4HTML3MBTL1 | |
| SCHEMBL13706027 | 0.72 | PTGS2 (0.43) | LMNAL3MBTL1ALDH1A1KDM4ESMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL29169563 | 0.71 | PTGS2 (0.42) | LMNAL3MBTL1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6006624 | 0.70 | — | — | |
| SCHEMBL11078493 | 0.69 | CES2 (0.58) | POLBLMNANAPRTP4HTML3MBTL1 | |
| SCHEMBL19668773 | 0.69 | ALDH1A1 (0.46) | LMNANAPRTP4HTML3MBTL1ALDH1A1 | |
| SCHEMBL16471838 | 0.69 | KDM4E (0.56) | LMNANAPRTP4HTML3MBTL1ALDH1A1 | |
| Methane SCHEMBL27768265 | 0.69 | ALDH1A1 (0.59) | POLBLMNANAPRTP4HTML3MBTL1 | |
| SCHEMBL24589250 | 0.68 | ALDH1A1 (0.49) | POLBLMNANAPRTP4HTML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004031168-A2 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF OPTICALLY ACTIVE 3-AMINO-1-(2-THIENYL)-1-PROPANOL DERIVATIVES | LONZA AG (CH) | 2004-04-15 | — | — | WO | disclosed |