Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.72 |
| ▸ | HTR2C | P28335 | 5/20 | 0.72 |
| ▸ | HTR6 | P50406 | 4/20 | 0.70 |
| ▸ | HTR1A | P08908 | 1/20 | 0.70 |
| ▸ | HTR1D | P28221 | 1/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.70 |
| ▸ | HTR7 | P34969 | 1/20 | 0.70 |
| ▸ | HTR5A | P47898 | 1/20 | 0.70 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831609 | 0.87 | HTR6 (0.57) | HTR2AHTR2CHTR6HTR1AHTR1D | |
| SCHEMBL7646413 | 0.84 | HTR2A (1.00) | HTR2AHTR2CHTR6HTR1AHTR1D | |
| SCHEMBL5763578 | 0.82 | HTR6 (1.00) | HTR2AHTR2CHTR6HTR1AHTR1D | |
| SCHEMBL29423321 | 0.82 | HTR6 (1.00) | HTR2AHTR2CHTR6HTR1AHTR1D | |
| SCHEMBL10832252 | 0.82 | HTR6 (0.49) | HTR2AHTR2CHTR6HTR1AHTR1D | |
| SCHEMBL28906368 | 0.82 | KDM4E (0.51) | HTR2AHTR2CTACR1PPARGHPGD | |
| SCHEMBL6929600 | 0.79 | PPARG (0.66) | TACR1PPARG | |
| SCHEMBL22161253 | 0.79 | TACR1 (0.49) | HTR2AHTR2CHTR6HTR1AHTR1D | |
| SCHEMBL24099472 | 0.78 | TACR1 (0.58) | SLC6A4TACR1PPARGMPO | |
| SCHEMBL28906355 | 0.77 | PTGS2 (0.53) | HTR2AHTR2CHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004041781-A1 | PREPARATION OF 3-AMINOALKYL-SUBSTITUTED INDOLE DERIVATIVES FROM PHENYLHYDRAZINES AND AMINOKETONES | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-05-21 | — | — | WO | disclosed |