Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 13/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | F13A1 | P00488 | 2/20 | 0.51 |
| ▸ | TGM1 | P22735 | 2/20 | 0.51 |
| ▸ | TGM6 | O95932 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823999 | 1.00 | DPP4 (0.53) | DPP4KCNH2DPP7TGM2DPP8 | |
| SCHEMBL7294359 | 0.92 | DPP4 (0.58) | DPP4KCNH2DPP7TGM2DPP8 | |
| Hydrochloric Acid SCHEMBL6767096 | 0.91 | DPP4 (0.58) | DPP4KCNH2DPP7TGM2DPP8 | |
| SCHEMBL6793150 | 0.91 | DPP4 (0.58) | DPP4KCNH2DPP7TGM2CTSL | |
| SCHEMBL9197198 | 0.89 | DPP4 (0.52) | DPP4KCNH2DPP7TGM2CTSL | |
| SCHEMBL30054191 | 0.88 | CTSL (0.56) | DPP4KCNH2DPP7TGM2CTSL | |
| SCHEMBL9003099 | 0.86 | CASP1 (0.58) | DPP4KCNH2DPP7CTSK | |
| SCHEMBL9003092 | 0.86 | CASP1 (0.58) | DPP4KCNH2DPP7CTSK | |
| SCHEMBL7145146 | 0.86 | CASP1 (0.58) | DPP4KCNH2DPP7CTSK | |
| SCHEMBL7145151 | 0.86 | CASP1 (0.58) | DPP4KCNH2DPP7CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076434-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | claimed |
| WO-2004076433-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | claimed |
| WO-2004076434-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | AIC (BE) | 2004-09-10 | — | — | WO | disclosed |