Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.58 |
| ▸ | TGM2 | P21980 | 14/20 | 0.56 |
| ▸ | F13A1 | P00488 | 2/20 | 0.55 |
| ▸ | TGM1 | P22735 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.53 |
| ▸ | TGM6 | O95932 | 1/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6767096 | 0.99 | DPP4 (0.58) | DPP4DPP8TGM2F13A1TGM1 | |
| SCHEMBL6824003 | 0.92 | DPP4 (0.53) | DPP4DPP8TGM2F13A1TGM1 | |
| SCHEMBL6823999 | 0.92 | DPP4 (0.53) | DPP4DPP8TGM2F13A1TGM1 | |
| SCHEMBL30054191 | 0.87 | CTSL (0.56) | DPP4TGM2F13A1TGM1DPP7 | |
| SCHEMBL6793150 | 0.87 | DPP4 (0.58) | DPP4TGM2F13A1TGM1DPP7 | |
| SCHEMBL9197198 | 0.85 | DPP4 (0.52) | DPP4TGM2F13A1TGM1DPP7 | |
| SCHEMBL15630554 | 0.84 | TGM2 (0.73) | DPP4DPP8TGM2F13A1TGM1 | |
| SCHEMBL15920174 | 0.84 | TGM2 (0.53) | DPP4DPP8TGM2F13A1TGM1 | |
| SCHEMBL25185922 | 0.83 | CASP1 (0.59) | DPP4DPP7KCNH2 | |
| SCHEMBL2856646 | 0.83 | DPP4 (0.64) | DPP4DPP8TGM2F13A1TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245568-A1 | Sulfonyl derivatives of amino acids and their use as inhibitors of dipeptidyl-peptidase IV (DPP IV) | Les Laboratoires Servier (FR) | 2002-10-02 | — | — | EP | disclosed |