Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16702064 | 0.80 | AR (0.49) | RAB9ASMN1; SMN2SIRT6ADRB1MAPT | |
| SCHEMBL9578136 | 0.80 | RAB9A (0.47) | RAB9ASMN1; SMN2ADRB1MAPTCRBN | |
| SCHEMBL1208101 | 0.80 | SMN1; SMN2 (0.72) | RAB9ASMN1; SMN2SIRT6ADRB1MAPT | |
| SCHEMBL6818839 | 0.77 | CTSG (0.42) | RAB9ASIRT6ADRB1MAPTCRBN | |
| SCHEMBL6824323 | 0.76 | SIRT6 (0.56) | SMN1; SMN2SIRT6ADRB1MAPTCRBN | |
| SCHEMBL8103968 | 0.70 | CRBN (0.48) | SIRT6ADRB1MAPTCRBNALDH1A1 | |
| SCHEMBL16701737 | 0.69 | SIRT6 (0.46) | RAB9ASIRT6ADRB1MAPTCRBN | |
| SCHEMBL11463857 | 0.69 | AR (0.59) | RAB9ASMN1; SMN2SIRT6ADRB1MAPT | |
| SCHEMBL31011685 | 0.69 | MAPT (0.56) | RAB9ASIRT6ADRB1MAPTCRBN | |
| SCHEMBL6821520 | 0.68 | SIRT6 (0.45) | RAB9ASMN1; SMN2SIRT6ADRB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067513-A1 | ANTAGONISTS FOR ALPHA-2 ADRENOCEPTORS | OY JUVANTIA PHARMA LTD (FI) | 2004-08-12 | — | — | WO | disclosed |