Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 3/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.33 |
| ▸ | NME2 | P22392 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824771 | 0.90 | CDK1 (0.38) | CDK1CDK2ALDH1A1MEN1HPGD | |
| SCHEMBL6824322 | 0.85 | TLR8 (0.36) | HTTSMN1; SMN2ALDH1A1MEN1HPGD | |
| SCHEMBL6821420 | 0.85 | CDK1 (0.43) | CDK1CDK2MEN1KMT2AMAPK14 | |
| SCHEMBL6923124 | 0.83 | CDK1 (0.53) | HTTSMN1; SMN2CDK1CDK2ALDH1A1 | |
| SCHEMBL6820704 | 0.81 | CDK1 (0.59) | HTTSMN1; SMN2CDK1CDK2ALDH1A1 | |
| SCHEMBL6824848 | 0.81 | CACNA1G (0.43) | CDK1CDK2HSD17B10KDM4E | |
| SCHEMBL6823612 | 0.81 | CDK1 (0.38) | HTTSMN1; SMN2CDK1CDK2MEN1 | |
| SCHEMBL6824730 | 0.79 | CDK1 (0.42) | HTTSMN1; SMN2CDK1CDK2ALDH1A1 | |
| SCHEMBL6826342 | 0.78 | KMT2A (0.40) | HTTCDK1CDK2ALDH1A1MEN1 | |
| SCHEMBL6824690 | 0.77 | IKBKB (0.35) | HTTCDK1CDK2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | claimed |
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | disclosed |