Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | CALCA | P06881 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824329 | 0.85 | HTT (0.36) | TLR8PIM2PIK3CDSMN1; SMN2HTT | |
| SCHEMBL6824771 | 0.74 | CDK1 (0.38) | TLR8HRH4ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6821420 | 0.70 | CDK1 (0.43) | TLR8DYRK1AHRH4RAD52MEN1 | |
| SCHEMBL6923124 | 0.69 | CDK1 (0.53) | SMN1; SMN2HTTALDH1A1KMT2A | |
| SCHEMBL12124182 | 0.67 | HTT (0.62) | SMN1; SMN2HTTALDH1A1HPGDTMEM97 | |
| SCHEMBL6824848 | 0.67 | CACNA1G (0.43) | HSD17B10KDM4E | |
| SCHEMBL6820704 | 0.67 | CDK1 (0.59) | SMN1; SMN2HTTADORA2AADORA1ALDH1A1 | |
| SCHEMBL15757860 | 0.66 | NUDT1 (0.54) | TLR8PIK3CDHRH4NUDT1ADORA2A | |
| SCHEMBL6823612 | 0.65 | CDK1 (0.38) | SMN1; SMN2HTTADORA2AADORA1HPGD | |
| SCHEMBL15757276 | 0.65 | NUDT1 (0.60) | TLR8HRH4NUDT1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | claimed |
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | disclosed |