Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 9/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821420 | 0.85 | CDK1 (0.43) | CDK1CDK2 | |
| SCHEMBL6923124 | 0.84 | CDK1 (0.53) | CDK1CDK2RAB9ANPC1 | |
| SCHEMBL6820797 | 0.82 | IL1B (0.41) | HSD17B10ACHE | |
| SCHEMBL6824771 | 0.81 | CDK1 (0.38) | HSD17B10CDK1CDK2 | |
| SCHEMBL6824329 | 0.81 | HTT (0.36) | HSD17B10KDM4ECDK1CDK2 | |
| SCHEMBL6820704 | 0.81 | CDK1 (0.59) | HSD17B10KDM4ECDK1CDK2 | |
| SCHEMBL6824167 | 0.76 | IKBKB (0.44) | CACNA1G | |
| SCHEMBL6824426 | 0.75 | CDK1 (0.43) | CDK1CDK2 | |
| SCHEMBL6823630 | 0.74 | CDK1 (0.49) | CDK1CDK2HRH3 | |
| SCHEMBL6918875 | 0.72 | CDK1 (0.55) | CDK1CDK2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | claimed |
| WO-2004080979-A1 | NOVEL 3-(2-AMINO-4-PYRIMIDINYL)-4-HYDROXYPHENYL KETONE DERIVATIVES | LG LIFE SCIENCES LTD. (KR) | 2004-09-23 | — | — | WO | disclosed |