Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 9/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ATF4 | P18848 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820561 | 0.89 | UTS2R (0.45) | HTR7UTS2RSSTR5KCNH2HTR1A | |
| SCHEMBL6381981 | 0.88 | HTR7 (0.49) | HTR7UTS2RSSTR5KCNH2HTR1A | |
| SCHEMBL7351045 | 0.86 | HTR7 (0.47) | HTR7UTS2RSSTR5KCNH2HTR1A | |
| SCHEMBL6824127 | 0.86 | HTR7 (0.45) | HTR7UTS2RSSTR5KCNH2HTR1A | |
| SCHEMBL6462162 | 0.84 | MCHR1 (0.43) | HTR7UTS2RSSTR5KCNH2HTR1A | |
| SCHEMBL6462165 | 0.84 | MCHR1 (0.43) | HTR7UTS2RSSTR5KCNH2HTR1A | |
| SCHEMBL7346919 | 0.83 | UTS2R (0.42) | HTR7UTS2RSSTR5KCNH2HTR1A | |
| SCHEMBL7347675 | 0.83 | UTS2R (0.49) | UTS2RSSTR5KCNH2MEN1KMT2A | |
| SCHEMBL6824089 | 0.82 | HTR7 (0.41) | HTR7UTS2RMEN1KMT2A | |
| SCHEMBL6823392 | 0.82 | HTR7 (0.49) | HTR7UTS2RHTR1AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | claimed |
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | disclosed |