Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381981 | 0.90 | HTR7 (0.49) | UTS2RHTR7HTR1ASSTR5KCNH2 | |
| SCHEMBL6824342 | 0.89 | HTR7 (0.43) | UTS2RHTR7HTR1ASSTR5KCNH2 | |
| SCHEMBL6824127 | 0.87 | HTR7 (0.45) | UTS2RHTR7HTR1AF10SSTR5 | |
| SCHEMBL6823289 | 0.87 | ALDH1A1 (0.37) | UTS2RHTR7KCNH2LMNAGLA | |
| SCHEMBL7351045 | 0.86 | HTR7 (0.47) | UTS2RHTR7HTR1ASSTR5KCNH2 | |
| SCHEMBL6462162 | 0.84 | MCHR1 (0.43) | UTS2RHTR7HTR1ASSTR5KCNH2 | |
| SCHEMBL6824089 | 0.84 | HTR7 (0.41) | UTS2RHTR7MEN1KMT2A | |
| SCHEMBL6462165 | 0.84 | MCHR1 (0.43) | UTS2RHTR7HTR1ASSTR5KCNH2 | |
| SCHEMBL7346919 | 0.83 | UTS2R (0.42) | UTS2RHTR7HTR1ASSTR5KCNH2 | |
| SCHEMBL6823392 | 0.83 | HTR7 (0.49) | UTS2RHTR7HTR1AACHEDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | claimed |
| WO-2004076444-A2 | NOVEL HYDROXYCOUMARANONE DERIVATIVES AS ANTITUMOR AND ANTIMETASTATIC | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-10 | — | — | WO | disclosed |