Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.77 |
| ▸ | MEN1 | O00255 | 8/20 | 0.77 |
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 5/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 3/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17466932 | 0.88 | MAPT (1.00) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL17466941 | 0.83 | MAPT (0.71) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL17466936 | 0.81 | MAPT (0.85) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL16705985 | 0.79 | KMT2A (0.65) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL1238796 | 0.79 | MEN1 (1.00) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL20824922 | 0.78 | KMT2A (0.80) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL20547658 | 0.77 | FBP1 (0.59) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL14198043 | 0.77 | FBP1 (0.59) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL21887201 | 0.77 | MAPT (0.77) | KMT2AALDH1A1MEN1MAPTKDM4E | |
| SCHEMBL9591757 | 0.77 | MAPT (0.77) | KMT2AALDH1A1MEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717076-B | Preparation method for obtaining methane functional product based on iron/light combined catalysis | 大连理工大学 | 2022-08-02 | — | — | CN | claimed |
| US-20240084308-A1 | FIBROTIC TREATMENT | MONASH UNIVERSITY (AU) | 2024-03-14 | — | — | US | disclosed |
| US-11834663-B2 | Fibrotic treatment | MONASH UNIVERSITY (AU) | 2023-12-05 | — | — | US | disclosed |
| US-11834663-B2 | Fibrotic treatment | MONASH UNIVERSITY (AU) | 2023-12-05 | — | — | US | disclosed |
| US-11834663-B2 | Fibrotic treatment | MONASH UNIVERSITY (AU) | 2023-12-05 | — | — | US | disclosed |
| CN-113717076-B | Preparation method for obtaining methane functional product based on iron/light combined catalysis | 大连理工大学 | 2022-08-02 | — | — | CN | disclosed |
| CN-114805124-A | Synthesis method of benzylidene malononitrile compound | 石家庄圣泰化工有限公司 | 2022-07-29 | — | — | CN | disclosed |
| EP-3553097-B1 | COPOLYMER AND OPTICAL FILM USING SAME | TOSOH CORP (JP) | 2022-05-04 | — | — | EP | disclosed |
| US-11306066-B2 | 4H-pyran compounds as insulin-regulated aminopeptidase (IRAP) inhibitors | MONASH UNIVERSITY (AU) | 2022-04-19 | — | — | US | disclosed |
| US-11225540-B2 | Copolymer and optical film using same | TOSOH CORPORATION (JP) | 2022-01-18 | — | — | US | disclosed |
| WO-2017015720-A1 | FIBROTIC TREATMENT | MONASH UNIVERSITY (AU) | 2017-02-02 | — | — | WO | disclosed |
| WO-2016179645-A1 | 4H-PYRAN COMPOUNDS AS INSULIN-REGULATED AMINOPEPTIDASE (IRAP) INHIBITORS | MONASH UNIVERSITY (AU) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016179645-A1 | 4H-PYRAN COMPOUNDS AS INSULIN-REGULATED AMINOPEPTIDASE (IRAP) INHIBITORS | MONASH UNIVERSITY (AU) | 2016-11-17 | — | — | WO | disclosed |
| US-9410035-B2 | Modified heterophasic polyolefin composition | MILLIKEN & COMPANY (US) | 2016-08-09 | — | — | US | disclosed |
| US-20160024289-A1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & COMPANY | 2016-01-28 | — | — | US | disclosed |
| WO-2013144191-A1 | SUBSTITUTED 2-AMINO-3-CYANOPYRIDINES AS INHIBITORS OF SODIUM-CALCIUM EXCHANGE AND USE THEREOF FOR CARDIOVASCULAR DISEASES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-03 | — | — | WO | disclosed |
| US-20040142821-A1 | Pesticide composition comprising malononitrile compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-22 | — | — | US | disclosed |
| EP-1385377-A1 | PESTICIDE COMPOSITION COMPRISING MALONONITRILE COMPOUNDS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002089579-A1 | PESTICIDE COMPOSITION COMPRISING MALONONITRILE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-11-14 | — | — | WO | disclosed |
| US-4184871-A | A,B-UNSATURATED NITRILE SENSITIZER | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1980-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11306066-B2 | 4H-pyran compounds as insulin-regulated aminopeptidase (IRAP) inhibitors | IAPP, ENPEP, DNPEP | KMT2A 1612/4885ALDH1A1 2853/4885MEN1 3983/4885 |
| US-11834663-B2 | Fibrotic treatment | MMP1, ENPEP, RNPEP | KMT2A 2797/4885ALDH1A1 1883/4885MEN1 4166/4885 |
| US-20040142821-A1 | Pesticide composition comprising malononitrile compounds | CBR1, CBR3, ME1 | KMT2A 3427/4885ALDH1A1 867/4885MEN1 1142/4885 |
| US-20240084308-A1 | FIBROTIC TREATMENT | MMP1, ENPEP, RNPEP | KMT2A 2797/4885ALDH1A1 1883/4885MEN1 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.