Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775852 | 0.79 | KMT2A (0.58) | KMT2AL3MBTL1PDE4APDE4BPDE4C | |
| SCHEMBL30160665 | 0.77 | MAPK1 (0.53) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28513461 | 0.77 | MAPK1 (0.53) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14846515 | 0.74 | KDM4E (0.51) | KMT2AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL1034613 | 0.73 | ALDH1A1 (0.56) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22022081 | 0.73 | KMT2A (0.60) | KMT2AL3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL1033487 | 0.68 | ALDH1A1 (0.55) | KMT2AKDM4EALDH1A1RAB9AMAPT | |
| SCHEMBL12324340 | 0.68 | CYP1A2 (0.49) | KDM4EPIM1ALDH1A1NPC1RAB9A | |
| SCHEMBL3751629 | 0.68 | KMT2A (1.00) | KMT2AKDM4EALDH1A1RAB9AMAPT | |
| SCHEMBL12365929 | 0.67 | L3MBTL1 (0.46) | KMT2AL3MBTL1KDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | claimed |
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |