Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 10/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919077 | 1.00 | S1PR3 (0.34) | S1PR3ARMGAT2CYP11B1CYP11B2 | |
| SCHEMBL6793038 | 0.83 | ALDH1A1 (0.41) | PGR | |
| SCHEMBL6794482 | 0.81 | PGR (0.49) | ARPGR | |
| SCHEMBL8339982 | 0.78 | PGR (0.41) | PGR | |
| SCHEMBL6791227 | 0.77 | MMP2 (0.41) | — | |
| SCHEMBL6789361 | 0.77 | MMP2 (0.41) | — | |
| SCHEMBL6791153 | 0.77 | MMP2 (0.41) | — | |
| SCHEMBL27584544 | 0.77 | MCL1 (0.41) | CYP11B1CYP11B2PGR | |
| SCHEMBL6789612 | 0.77 | PGR (0.36) | ARPGR | |
| SCHEMBL8343005 | 0.76 | MMP3 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024060-A2 | METALLOPROTEINASE INHIBITORS AND INTERMEDIATES FOR PREPARATION THEREOF | ASTRAZENECA AB (SE) | 2004-03-25 | — | — | WO | claimed |