Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.33 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31063422 | 0.80 | ACHE (0.40) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6828638 | 0.78 | ILK (0.34) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1094735 | 0.78 | TUBB1 (0.34) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL335274 | 0.78 | TUBB1 (0.34) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2467633 | 0.78 | TUBB1 (0.34) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23461783 | 0.76 | TUBB4A (0.37) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29919096 | 0.76 | TUBB4A (0.37) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL17622095 | 0.76 | TAAR1 (0.41) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3537612 | 0.73 | TUBB1 (0.34) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31063374 | 0.73 | GABRA1 (0.34) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073612-A2 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO. INC. (US) | 2004-09-02 | — | — | WO | disclosed |