Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2964533 | 0.84 | NCEH1 (0.47) | NCEH1LMNAL3MBTL1ALDH1A1CYP2A6 | |
| SCHEMBL4609033 | 0.81 | CA2 (0.61) | LMNAALDH1A1CA2CA1CA9 | |
| SCHEMBL18532783 | 0.81 | NCEH1 (0.45) | NCEH1LMNAL3MBTL1ALDH1A1CYP2A6 | |
| SCHEMBL2964535 | 0.81 | GAA (0.51) | NCEH1LMNAL3MBTL1ALDH1A1CYP2A6 | |
| SCHEMBL32665362 | 0.81 | NCEH1 (0.45) | NCEH1LMNAL3MBTL1ALDH1A1CYP2A6 | |
| SCHEMBL31499216 | 0.80 | PTGS2 (0.54) | LMNAL3MBTL1ALDH1A1CYP2A6CA2 | |
| SCHEMBL1395608 | 0.80 | CA2 (0.66) | LMNAL3MBTL1ALDH1A1CYP2A6CA2 | |
| SCHEMBL28528484 | 0.79 | CA2 (0.59) | LMNAALDH1A1CA2CA1CA9 | |
| Potassium Ion SCHEMBL4607951 | 0.79 | PTGS2 (0.47) | NCEH1LMNAL3MBTL1ALDH1A1CYP2A6 | |
| SCHEMBL1395599 | 0.78 | CYP2A6 (0.52) | LMNAALDH1A1CYP2A6CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004024060-A2 | METALLOPROTEINASE INHIBITORS AND INTERMEDIATES FOR PREPARATION THEREOF | ASTRAZENECA AB (SE) | 2004-03-25 | — | — | WO | disclosed |