Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.61 |
| ▸ | CA9 | Q16790 | 5/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17287795 | 0.94 | CA2 (0.55) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL575589 | 0.87 | CA2 (0.52) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL11572629 | 0.87 | LMNA (0.62) | CA2CA9CA1CA12MEN1 | |
| SCHEMBL6824930 | 0.81 | NCEH1 (0.49) | CA2CA9CA1CA12ALDH1A1 | |
| SCHEMBL27746568 | 0.80 | CA2 (0.67) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL3838977 | 0.80 | CA2 (0.58) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL6941035 | 0.78 | CA1 (0.64) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL168170 | 0.78 | CA2 (0.64) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL27593450 | 0.77 | CA2 (0.57) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL6037 | 0.76 | CA2 (0.48) | CA2CA9CA1CA12MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699072-B | Process for the preparation of 7H-pyrrolo [2,3-D ] pyrimidine compounds | 硕腾服务有限责任公司 | 2021-02-26 | — | — | CN | claimed |
| CN-108699072-B | Process for the preparation of 7H-pyrrolo [2,3-D ] pyrimidine compounds | 硕腾服务有限责任公司 | 2021-02-26 | — | — | CN | disclosed |
| EP-2949655-B1 | REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND | HOKKO CHEM IND CO (JP) | 2019-05-15 | — | — | EP | disclosed |
| US-9707551-B2 | Reaction catalyst for cross-coupling and method for manufacturing aromatic compound | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-07-18 | — | — | US | disclosed |
| CN-101835728-B | Compounds for imaging, diagnosing and/or treating central nervous system diseases or tumors | BAYER SCHERING PHARMA AG (DE) | 2016-03-09 | — | — | CN | disclosed |
| CN-105175293-A | Compounds for imaging, diagnosing and/or treating central nervous system diseases or tumors | BAYER SCHERING PHARMA AG | 2015-12-23 | — | — | CN | disclosed |
| US-20150360214-A1 | REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |
| EP-2949655-A1 | REACTION CATALYST FOR CROSS COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND | Hokko Chemical Industry Co., Ltd. (JP) | 2015-12-02 | — | — | EP | disclosed |
| CN-105008378-A | Reaction catalyst for cross coupling and method for manufacturing aromatic compound | HOKKO CHEM IND CO | 2015-10-28 | — | — | CN | disclosed |
| CN-1854133-B | Heterocycle-bearing onium salts | WAKO PURE CHEM IND LTD | 2010-11-10 | — | — | CN | disclosed |
| US-5856339-A | POST-MENOPAUSAL SYNDROME, AND UTERINE FIBROID DISEASE, ENDOMETRIOSIS, AND AORTAL SMOOTH MUSCLE CELL PROLIFERATION. | ELI LILLY AND COMPANY (US) | 1999-01-05 | — | — | US | disclosed |
| US-5856340-A | 2-PHENYL-3-/ALKOXYPHENOXY OR PHENYLTHIO/BENZOTHIOPHENES | ELI LILLY AND COMPANY (US) | 1999-01-05 | — | — | US | disclosed |
| WO-1998045287-A1 | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS WITH SELECTIVE ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 1998-10-15 | — | — | WO | disclosed |
| WO-1998045286-A1 | PREVENTION OF BREAST CANCER WITH SELECTIVE ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 1998-10-15 | — | — | WO | disclosed |
| WO-1998045288-A1 | TREATMENT OR PROPHYLAXIS OF PROSTATIC CANCER AND BENIGN PROSTATIC HYPERPLASIA WITH SELECTIVE ESTROGEN RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 1998-10-15 | — | — | WO | disclosed |
| US-5723474-A | TREATING POST-MENOPAUSAL SYNDROME, UTERINE FIBROID DISEASE, ENDOMETRIOSIS, AND AORTAL SMOOTH MUSCLE CELL PROLIFERATION; ANTIESTROGENS | ELI LILLY AND COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| CN-1159448-A | Benzothiophene compounds, intermediates, compositions, and methods | LILLY CO ELI (US) | 1997-09-17 | — | — | CN | disclosed |
| EP-0729956-A1 | Benzothiophene compounds, intermediates, compositions, and methods | ELI LILLY AND COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| EP-0001495-A1 | Peroxygen bleaching and compositions therefor | FMC Corporation (US) | 1979-04-18 | — | — | EP | disclosed |
| US-4128490-A | BLEACHES | FMC CORPORATION (US) | 1978-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150360214-A1 | REACTION CATALYST FOR CROSS-COUPLING AND METHOD FOR MANUFACTURING AROMATIC COMPOUND | ALK, HRH4, HRH3 | CA2 163/4885CA9 411/4885CA1 952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.