Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.59 |
| ▸ | CA9 | Q16790 | 5/20 | 0.59 |
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP7 | P09237 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP14 | P50281 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4609033 | 0.98 | CA2 (0.61) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL17287795 | 0.91 | CA2 (0.55) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL575589 | 0.85 | CA2 (0.52) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL11572629 | 0.85 | LMNA (0.62) | CA2CA9CA1CA12MEN1 | |
| SCHEMBL6824930 | 0.79 | NCEH1 (0.49) | CA2CA9CA1CA12ALDH1A1 | |
| SCHEMBL3838977 | 0.78 | CA2 (0.58) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL27746568 | 0.78 | CA2 (0.67) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL22688923 | 0.76 | CA2 (0.56) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL6941035 | 0.76 | CA1 (0.64) | CA2CA9CA1CA12MMP2 | |
| SCHEMBL168170 | 0.76 | CA2 (0.64) | CA2CA9CA1CA12MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699072-B | Process for the preparation of 7H-pyrrolo [2,3-D ] pyrimidine compounds | 硕腾服务有限责任公司 | 2021-02-26 | — | — | CN | disclosed |