SCHEMBL6825073

SCHEMBL6825073

CC(C)(CNC(=O)Nc1ccc(S(C)(=O)=O)cc1Cl)CC(=O)N(CC(=O)NO)CC1CCCC1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PDK1 Q15118 4/20 0.39
PDK2 Q15119 4/20 0.39
PDK3 Q15120 4/20 0.39
PDK4 Q16654 4/20 0.39
RORC P51449 2/20 0.37
MMP3 P08254 1/20 0.35
F10 P00742 1/20 0.35
CA1 P00915 5/20 0.35
CA2 P00918 5/20 0.35
SMO Q99835 1/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPT P10636 1/20 0.34
ALDH3A1 P30838 1/20 0.34
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34
CA4 P22748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825485 0.89 RAB9A (0.43) MEN1KMT2AALDH1A1MAPT
SCHEMBL6824982 0.88 RAB9A (0.41) KMT2AALDH1A1MAPT
SCHEMBL6822311 0.86 NPC1 (0.40)
SCHEMBL6825386 0.84 TP53 (0.38) MEN1KMT2AALDH1A1MAPT
SCHEMBL6827642 0.84 NPC1 (0.38)
SCHEMBL6825911 0.82 TP53 (0.38) MEN1KMT2APDK1PDK2PDK3
SCHEMBL6825899 0.82 RAB9A (0.42) MEN1KMT2AALDH1A1MAPT
SCHEMBL6825069 0.81 PDK1 (0.39) MEN1KMT2APDK1PDK2PDK3
SCHEMBL6825402 0.80 ALDH1A1 (0.49) MEN1KMT2AALDH1A1MAPT
SCHEMBL7066677 0.80 SMN1; SMN2 (0.38) MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004087643-A1 DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME PROMEDITECH INC. (KR) 2004-10-14 WO claimed