SCHEMBL6825677

SCHEMBL6825677

CC(C)[C@H](NC(=O)Nc1ccccc1Cl)C(=O)N(CCC1CCCC1)CC(=O)NO

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 3/20 0.48
TAS1R1 Q7RTX1 3/20 0.48
ANPEP P15144 1/20 0.44
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
ALDH1A1 P00352 2/20 0.37
POLB P06746 2/20 0.37
MMP2 P08253 2/20 0.37
MMP3 P08254 2/20 0.37
BMP1 P13497 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
CTSD P07339 1/20 0.36
BACE1 P56817 1/20 0.36
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825493 0.91 TAS1R3 (0.50) TAS1R3TAS1R1ANPEPNPC1RAB9A
SCHEMBL6822349 0.89 ALDH1A1 (0.40) TAS1R3TAS1R1ALDH1A1POLBMMP3
SCHEMBL6822114 0.89 RAB9A (0.43) TAS1R3TAS1R1NPC1RAB9AALDH1A1
SCHEMBL6825851 0.89 TAS1R3 (0.46) TAS1R3TAS1R1ANPEPNPC1RAB9A
SCHEMBL6827631 0.89 TAS1R3 (0.47) TAS1R3TAS1R1ANPEPNPC1RAB9A
SCHEMBL6827879 0.88 TDP1 (0.49) TAS1R3TAS1R1ANPEPMMP3
SCHEMBL6825157 0.85 ANPEP (0.52) TAS1R3TAS1R1ANPEPALDH1A1POLB
SCHEMBL6825406 0.85 ALDH1A1 (0.41) NPC1RAB9AALDH1A1POLBMMP2
SCHEMBL6822417 0.83 ALDH1A1 (0.51) ALDH1A1POLBNPSR1CYP2C19
SCHEMBL6824956 0.83 LMNA (0.40) ALDH1A1POLBMMP3NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004087643-A1 DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME PROMEDITECH INC. (KR) 2004-10-14 WO claimed