Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.49 |
| ▸ | GABRD | O14764 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.49 |
| ▸ | GABRE | P78334 | 1/20 | 0.49 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.49 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.49 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825859 | 0.85 | KMT2A (0.53) | GABRPGABRDTNKSPARP1GABRA1 | |
| SCHEMBL28356532 | 0.82 | LMNA (0.58) | TNKSPARP1TNKS2CHRM2CHRM4 | |
| SCHEMBL28212030 | 0.81 | MAPK14 (0.55) | MAPK14PTGS2PTGS1GABRPGABRD | |
| SCHEMBL22960257 | 0.80 | CHRM2 (0.53) | TNKSCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL29839901 | 0.79 | PTGS2 (0.55) | MAPK14PTGS2PTGS1GABRPGABRD | |
| SCHEMBL28352973 | 0.79 | MAPK14 (0.52) | MAPK14PTGS2PTGS1GABRPGABRD | |
| SCHEMBL25824780 | 0.76 | ANO1 (0.43) | TNKSCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28088149 | 0.75 | TNKS (0.49) | MAPK14PTGS2PTGS1TNKSMEN1 | |
| SCHEMBL18341912 | 0.75 | AR (0.52) | MAPK14PTGS2PTGS1MEN1CYP3A4 | |
| SCHEMBL12825536 | 0.73 | ADORA3 (0.77) | MAPK14PTGS2PTGS1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089939-A1 | CONDENSED FURAN DERIVATIVES AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-10-21 | — | — | WO | disclosed |