Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 1.00 |
| ▸ | GNRHR | P30968 | 1/20 | 0.63 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6825803 | 0.85 | DRD2 (1.00) | DRD2GNRHRDRD1 | |
| SCHEMBL6820733 | 0.81 | DRD2 (1.00) | DRD2HTR1AHTR2A | |
| SCHEMBL23097603 | 0.77 | DRD2 (0.68) | DRD2HTR1AHTR2A | |
| SCHEMBL28809903 | 0.76 | DRD2 (0.62) | DRD2HTR2A | |
| SCHEMBL29785745 | 0.76 | DRD2 (0.62) | DRD2HTR2A | |
| SCHEMBL11262793 | 0.73 | RECQL (0.66) | DRD2HTR2A | |
| SCHEMBL1253143 | 0.73 | SIGMAR1 (0.69) | DRD2HTR1A | |
| SCHEMBL2095954 | 0.73 | SIGMAR1 (0.69) | DRD2HTR1AHTR2A | |
| SCHEMBL21669396 | 0.73 | SIGMAR1 (0.69) | DRD2HTR1AHTR2A | |
| SCHEMBL11285131 | 0.73 | DRD2 (0.69) | DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004035534-A2 | NOVEL COMPOUNDS HAVING A DOPAMINERGIC AND/OR SEROTONINERGIC ACTIVITY | PROTEOSYS AG (DE) | 2004-04-29 | — | — | WO | disclosed |