Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 4/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10616528 | 0.77 | L3MBTL1 (0.60) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL3267161 | 0.76 | F2 (0.62) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7948519 | 0.73 | L3MBTL1 (0.55) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7371173 | 0.73 | SLC1A3 (0.59) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6825950 | 0.73 | NPC1 (0.52) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL29492938 | 0.73 | L3MBTL1 (0.64) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL11162145 | 0.73 | L3MBTL1 (0.64) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6848743 | 0.73 | KAT6A (0.63) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL11032473 | 0.73 | L3MBTL1 (0.62) | L3MBTL1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL10448919 | 0.72 | L3MBTL1 (0.59) | L3MBTL1LMNASMN1; SMN2KAT6AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067522-A1 | AZAPHENYLALANINE DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | LEK PHARMACEUTICALS D.D. (SI) | 2004-08-12 | — | — | WO | disclosed |