Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.59 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.59 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 4/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.56 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10830548 | 0.87 | ADAMTS4 (0.66) | SLC1A3SLC1A2SLC1A1F2LARS1 | |
| SCHEMBL8319592 | 0.87 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC1A1F2PRSS1 | |
| SCHEMBL7322447 | 0.87 | ADAMTS4 (0.66) | SLC1A3SLC1A2SLC1A1F2LARS1 | |
| SCHEMBL10830564 | 0.85 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1F2PRSS1 | |
| SCHEMBL10830562 | 0.85 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1F2PRSS1 | |
| SCHEMBL8619578 | 0.83 | KMT2A (0.48) | F2PRSS1PRSS2PRSS3KAT6A | |
| SCHEMBL3687103 | 0.81 | ADAMTS4 (0.61) | SLC1A3SLC1A2SLC1A1LARS1L3MBTL1 | |
| SCHEMBL791357 | 0.81 | ADAMTS4 (0.61) | SLC1A3SLC1A2SLC1A1LARS1L3MBTL1 | |
| SCHEMBL3692936 | 0.81 | L3MBTL1 (0.66) | SLC1A3SLC1A2SLC1A1F2PRSS1 | |
| SCHEMBL6008513 | 0.80 | L3MBTL1 (0.64) | SLC1A3SLC1A2SLC1A1F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997049673-A1 | SELECTIVE THROMBIN INHIBITORS | LG CHEMICAL LTD. (KR) | 1997-12-31 | — | — | WO | claimed |
| WO-2001019808-A1 | CHEMICAL COMPOUNDS AND COMPOSITIONS AND THEIR USE AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | disclosed |