Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28252160 | 0.81 | HSD11B1 (0.50) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL10616528 | 0.77 | L3MBTL1 (0.60) | NPC1RAB9AF2PRSS1PRSS2 | |
| SCHEMBL10449076 | 0.76 | LMNA (0.58) | NPC1RAB9AF2PRSS1PRSS2 | |
| SCHEMBL29212110 | 0.76 | NPC1 (0.61) | NPC1RAB9AALDH1A1HTTL3MBTL1 | |
| SCHEMBL29964126 | 0.76 | NPC1 (0.61) | NPC1RAB9AALDH1A1HTTL3MBTL1 | |
| SCHEMBL7774832 | 0.75 | NPC1 (0.57) | NPC1RAB9AALDH1A1HTTL3MBTL1 | |
| SCHEMBL9642217 | 0.75 | NPC1 (0.48) | NPC1RAB9AF2PRSS1PRSS2 | |
| SCHEMBL10449070 | 0.75 | LMNA (0.54) | NPC1RAB9AHTTL3MBTL1LMNA | |
| SCHEMBL6825948 | 0.73 | L3MBTL1 (0.55) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL3267161 | 0.73 | F2 (0.62) | F2PRSS1PRSS2PRSS3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067522-A1 | AZAPHENYLALANINE DERIVATIVES AND THEIR USE AS ANTITHROMBOTIC AGENTS | LEK PHARMACEUTICALS D.D. (SI) | 2004-08-12 | — | — | WO | disclosed |