Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499683 | 0.71 | PTGS2 (0.42) | TP53NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6678240 | 0.70 | SLC6A2 (0.45) | SLC6A2NPC1RAB9ALMNA | |
| SCHEMBL6488746 | 0.70 | MAPT (0.60) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6676886 | 0.69 | APOB (0.46) | KDM4E | |
| SCHEMBL6677499 | 0.68 | NPC1 (0.50) | SLC6A2NPC1RAB9ADHODHTHRB | |
| SCHEMBL6491055 | 0.68 | APOB (0.60) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6493029 | 0.68 | SLC6A3 (0.55) | SLC6A2SMN1; SMN2ALDH1A1SLC6A3SLC6A4 | |
| SCHEMBL6502875 | 0.68 | SLC6A3 (0.55) | SLC6A2SMN1; SMN2ALDH1A1SLC6A3SLC6A4 | |
| SCHEMBL6491174 | 0.68 | SLC6A3 (0.55) | SLC6A2SMN1; SMN2ALDH1A1SLC6A3SLC6A4 | |
| SCHEMBL6502878 | 0.68 | SLC6A3 (0.55) | SLC6A2SMN1; SMN2ALDH1A1SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004039795-A2 | AMIDE COMPOUNDS FOR THE TREATMENT OF HYPERLIPIDEMIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-13 | — | — | WO | disclosed |