Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5554257 | 0.98 | ALDH1A1 (0.39) | ALDH1A1THRBTSHR | |
| SCHEMBL17707265 | 0.87 | ALDH1A1 (0.34) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10748836 | 0.77 | ALDH1A1 (0.41) | ALDH1A1THRBTSHR | |
| SCHEMBL9347706 | 0.76 | ALDH1A1 (0.44) | ALDH1A1THRBTSHR | |
| Hydrochloric Acid SCHEMBL27761081 | 0.74 | MAPT (0.43) | ALDH1A1THRBTSHR | |
| Hydrochloric Acid SCHEMBL4764541 | 0.73 | TGFBR1 (0.43) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL61003 | 0.73 | TGFBR1 (0.43) | ALDH1A1 | |
| SCHEMBL1993143 | 0.71 | TSHR (0.41) | ALDH1A1THRBTSHR | |
| Hydrochloric Acid SCHEMBL4920381 | 0.71 | TGFBR1 (0.42) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6826516 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3015481-B1 | AQUEOUS DISPERSION OF FLUORINATED COPOLYMER | UNIMATEC CO LTD (JP) | 2018-08-22 | — | — | EP | disclosed |
| US-10023733-B2 | Aqueous dispersion of fluorine-containing copolymer | UNIMATEC CO., LTD. (JP) | 2018-07-17 | — | — | US | disclosed |
| US-20160185948-A1 | AQUEOUS DISPERSION OF FLUORINE-CONTAINING COPOLYMER | UNIMATEC CO., LTD. (JP) | 2016-06-30 | — | — | US | disclosed |
| EP-3015481-A1 | AQUEOUS DISPERSION OF FLUORINATED COPOLYMER | Unimatec Co., Ltd. (JP) | 2016-05-04 | — | — | EP | disclosed |
| EP-1084295-B1 | A PROCESS FOR THE PRODUCTION OF PAPER | AKZO NOBEL NV (NL) | 2004-01-07 | — | — | EP | disclosed |
| US-20020139502-A1 | Process for the production of paper | HALLSTROM HANS (SE) | 2002-10-03 | — | — | US | disclosed |
| EP-1084295-A2 | A PROCESS FOR THE PRODUCTION OF PAPER | Akzo Nobel N.V. (NL) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999055962-A2 | A PROCESS FOR THE PRODUCTION OF PAPER | AKZO NOBEL N.V. (NL) | 1999-11-04 | — | — | WO | disclosed |