Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPRG | P23470 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826142 | 0.83 | TERT (0.51) | TERTALDH1A1LMNAHPGDTSHR | |
| SCHEMBL6829436 | 0.82 | TERT (0.52) | TERTALDH1A1POLBLMNATSHR | |
| SCHEMBL6829215 | 0.81 | TERT (0.58) | TERTALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL6831211 | 0.80 | TERT (0.48) | TERTGRM4ALDH1A1TSHRMAPT | |
| SCHEMBL6829200 | 0.79 | TERT (0.54) | TERTALDH1A1POLBLMNATSHR | |
| SCHEMBL6826092 | 0.78 | TERT (0.55) | TERTALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL6829795 | 0.78 | TERT (0.53) | TERTALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL6831124 | 0.77 | TERT (0.51) | TERTALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL6828953 | 0.77 | TERT (0.51) | TERTALDH1A1POLBLMNATSHR | |
| SCHEMBL6830047 | 0.77 | MAPT (0.41) | TERTALDH1A1POLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |