Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 2/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829436 | 0.86 | TERT (0.52) | TERTMAPTLMNAL3MBTL1MGAM | |
| SCHEMBL6830047 | 0.84 | MAPT (0.41) | TERTMAPTLMNAHTTNPSR1 | |
| SCHEMBL6828953 | 0.84 | TERT (0.51) | TERTMAPTLMNAALDH1A1TSHR | |
| SCHEMBL6831124 | 0.84 | TERT (0.51) | TERTMAPTLMNANPC1RAB9A | |
| SCHEMBL6826233 | 0.83 | TERT (0.54) | TERTMAPTLMNAHTTL3MBTL1 | |
| SCHEMBL6829215 | 0.82 | TERT (0.58) | TERTMAPTL3MBTL1MGAMGAA | |
| SCHEMBL6829200 | 0.80 | TERT (0.54) | TERTLMNAL3MBTL1MGAMGAA | |
| SCHEMBL6828648 | 0.80 | TERT (0.54) | TERTMAPTLMNANPC1HTT | |
| SCHEMBL6826092 | 0.79 | TERT (0.55) | TERTMAPTLMNANPC1HTT | |
| SCHEMBL6829795 | 0.78 | TERT (0.53) | TERTMAPTLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |