Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 5/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830047 | 0.84 | MAPT (0.41) | TERTMAOBMAOAMAPTSMN1; SMN2 | |
| SCHEMBL6828953 | 0.84 | TERT (0.51) | TERTMAOBMAOAMAPTPOLB | |
| SCHEMBL6826142 | 0.84 | TERT (0.51) | TERTMAPTNPC1RAB9AMGAM | |
| SCHEMBL6828648 | 0.80 | TERT (0.54) | TERTMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6826233 | 0.77 | TERT (0.54) | TERTMAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL6829200 | 0.77 | TERT (0.54) | TERTPOLBMGAMGAASI | |
| SCHEMBL6829436 | 0.76 | TERT (0.52) | TERTMAPTPOLBMGAMGAA | |
| SCHEMBL6829246 | 0.73 | KMT2A (0.51) | MAPTSMN1; SMN2NPC1ALDH1A1TSHR | |
| SCHEMBL6829215 | 0.73 | TERT (0.58) | TERTMAOBMAOAMAPTPOLB | |
| SCHEMBL6829660 | 0.73 | TERT (0.58) | TERTMAPTSMN1; SMN2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |