Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829215 | 0.87 | TERT (0.58) | TERTALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL6826142 | 0.86 | TERT (0.51) | TERTALDH1A1TSHRMAPTTDP1 | |
| SCHEMBL6829795 | 0.83 | TERT (0.53) | TERTALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL6826233 | 0.82 | TERT (0.54) | TERTALDH1A1TSHRMAPTPOLB | |
| SCHEMBL6829200 | 0.79 | TERT (0.54) | TERTALDH1A1TSHRKDM4EPOLB | |
| SCHEMBL6923697 | 0.79 | TERT (0.46) | TERTALDH1A1KDM4EPOLBTDP1 | |
| SCHEMBL6826092 | 0.78 | TERT (0.55) | TERTALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL6828953 | 0.76 | TERT (0.51) | TERTALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL6830047 | 0.76 | MAPT (0.41) | TERTALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL6831124 | 0.76 | TERT (0.51) | TERTALDH1A1TSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |