Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826264 | 0.91 | SLC6A4 (0.39) | SLC6A4LTA4HKMT2ASLC6A9SLC6A2 | |
| SCHEMBL6826640 | 0.90 | LTA4H (0.45) | SLC6A4LTA4HKMT2ASLC6A9ALDH1A1 | |
| SCHEMBL6823045 | 0.81 | SLC6A4 (0.41) | SLC6A4LTA4HKMT2ASLC6A9GCGR | |
| SCHEMBL7214342 | 0.79 | SLC6A4 (0.45) | SLC6A4SLC6A9ALDH1A1CYP2D6MAPT | |
| SCHEMBL6826258 | 0.79 | SLC6A9 (0.62) | SLC6A9ALDH1A1CYP2D6MAPTCYP2C9 | |
| SCHEMBL6826677 | 0.79 | SLC6A4 (0.43) | SLC6A4LTA4HKMT2ASLC6A9ALDH1A1 | |
| SCHEMBL6826424 | 0.76 | GCGR (0.38) | SLC6A4SLC6A9ALDH1A1CYP2D6MAPT | |
| SCHEMBL7208064 | 0.73 | SLC6A4 (0.46) | SLC6A4LTA4HSLC6A9HPGDGCGR | |
| SCHEMBL6753047 | 0.73 | SLC7A5 (0.41) | SLC6A4KMT2ASLC6A9ALDH1A1CYP2D6 | |
| SCHEMBL6256697 | 0.73 | SLC6A9 (0.42) | SLC6A4KMT2ASLC6A9ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294677-B1 | BENZOPHENONES AND SULFONES AS INHIBITORS OF GLYCINE UPTAKE | PFIZER PROD INC (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1294677-A1 | BENZOPHENONES AND SULFONES AS INHIBITORS OF GLYCINE UPTAKE | Pfizer Products Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| US-6506780-B2 | Benzophenones and sulfones as inhibitors of glycine uptake | PFIZER INC. | 2003-01-14 | — | — | US | disclosed |
| US-20020052401-A1 | Benzophenones and sulfones as inhibitors of glycine uptake | PFIZER INC. | 2002-05-02 | — | — | US | disclosed |
| WO-2002000602-A1 | BENZOPHENONES AND SULFONES AS INHIBITORS OF GLYCINE UPTAKE | PFIZER PRODUCTS INC. (US) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052401-A1 | Benzophenones and sulfones as inhibitors of glycine uptake | SLC6A1, SLC6A5, SLC1A2 | SLC6A4 7/4885LTA4H 4297/4885KMT2A 1450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.