Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR6 | P50406 | 10/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR1D | P28221 | 2/20 | 0.52 |
| ▸ | HTR1E | P28566 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | HTR5A | P47898 | 2/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.52 |
| ▸ | HTR3B | O95264 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR1F | P30939 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2061056 | 0.82 | KDM4E (0.50) | — | |
| SCHEMBL10411871 | 0.78 | HTR2A (0.55) | HTR2AHTR6HTR2CHTR2BHTR1A | |
| Hydrochloric Acid SCHEMBL8507682 | 0.78 | HTR2A (0.55) | HTR2AHTR6HTR2CHTR2BHTR1A | |
| SCHEMBL24310155 | 0.78 | HTR2A (0.55) | HTR2AHTR6HTR2CHTR2BHTR1A | |
| SCHEMBL6831444 | 0.77 | HTR6 (0.39) | HTR2AHTR6HTR2CHTR2BHTR1A | |
| SCHEMBL15935626 | 0.77 | POLB (0.49) | — | |
| Hydrochloric Acid SCHEMBL10412386 | 0.77 | HTR2A (0.54) | HTR2AHTR6HTR2CHTR2BHTR1A | |
| SCHEMBL8129995 | 0.75 | KDM4E (0.45) | HTR2A | |
| SCHEMBL15569140 | 0.75 | KMT2A (0.51) | HTR2AHTR6HTR2CHTR2BHTR1A | |
| SCHEMBL16952197 | 0.74 | KDM4E (0.44) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043921-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-ARYL-3-HYDROXYMETHYL-1-METHYLPIPERIDINES. | NATCO PHARMA LIMITED (IN) | 2004-05-27 | — | — | WO | disclosed |