Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059150 | 0.82 | HTR1A (0.41) | HTR6TAAR1HTR2AHTR2CHTR1A | |
| SCHEMBL30150898 | 0.80 | AMY1A (0.43) | TAAR1HTTCYP1A2 | |
| SCHEMBL233241 | 0.80 | AMY1A (0.43) | TAAR1HTTCYP1A2 | |
| SCHEMBL10949866 | 0.79 | AMY1A (0.52) | HTR6TAAR1HTR2AHTR2CHTR1A | |
| SCHEMBL24124009 | 0.79 | PYCR1 (0.47) | HTR6TAAR1HTTSMN1; SMN2CYP1A2 | |
| SCHEMBL7057925 | 0.78 | SIGMAR1 (0.45) | HTR6TAAR1SMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL6826542 | 0.77 | HTR2A (0.54) | HTR6HTR2AHTR2CHTR1AHTR2B | |
| SCHEMBL10411876 | 0.76 | TAAR1 (0.40) | HTR6TAAR1HTR2AHTR2CHTR1A | |
| SCHEMBL24691168 | 0.74 | TAAR1 (0.40) | TAAR1HTTSLC6A4PSEN1PSEN2 | |
| SCHEMBL12509537 | 0.74 | AMY1A (0.39) | TAAR1HTTPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043921-A1 | NOVEL PROCESS FOR THE PREPARATION OF 4-ARYL-3-HYDROXYMETHYL-1-METHYLPIPERIDINES. | NATCO PHARMA LIMITED (IN) | 2004-05-27 | — | — | WO | disclosed |