Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 3/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 10/20 | 0.39 |
| ▸ | EGFR | P00533 | 5/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.37 |
| ▸ | ERBB4 | Q15303 | 4/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6239978 | 0.88 | EGFR (0.47) | MKNK1EGFRERBB2ERBB4JAK3 | |
| Formic Acid SCHEMBL6826685 | 0.81 | EGFR (0.45) | PIP4K2AMKNK1EGFRERBB2ERBB4 | |
| SCHEMBL6237787 | 0.74 | EGFR (0.47) | PIP4K2AEGFRERBB2ERBB4 | |
| Hydrochloric Acid SCHEMBL6825273 | 0.73 | EGFR (0.43) | EGFRERBB2ERBB4LRRK2 | |
| SCHEMBL6234112 | 0.70 | ALDH1A1 (0.41) | PIP4K2AMKNK1EGFRERBB2 | |
| SCHEMBL6258587 | 0.70 | ERBB2 (0.44) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL6232747 | 0.69 | ERBB2 (0.48) | EGFRERBB2ERBB4JAK3 | |
| SCHEMBL6255788 | 0.68 | EGFR (0.41) | PIP4K2AEGFRERBB2 | |
| SCHEMBL6238337 | 0.66 | EGFR (0.81) | EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL6239291 | 0.66 | EGFR (0.80) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | claimed |
| WO-2005007083-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |