Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827215 | 0.81 | NR1I2 (0.38) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL7131529 | 0.79 | MLLT3 (0.40) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL6924594 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL6920288 | 0.76 | L3MBTL1 (0.53) | RAB9AATMLMNATP53SMN1; SMN2 | |
| SCHEMBL6827332 | 0.76 | NPC1 (0.44) | NPC1RAB9ANLRP3ADORA1ADORA3 | |
| SCHEMBL6919056 | 0.76 | MLLT3 (0.44) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL7131791 | 0.75 | MLLT3 (0.39) | NPC1RAB9AATMFAAHLMNA | |
| SCHEMBL6923871 | 0.75 | L3MBTL1 (0.54) | NPC1RAB9AATMLMNATP53 | |
| SCHEMBL6827816 | 0.74 | HTT (0.43) | ATMTP53 | |
| SCHEMBL6827359 | 0.73 | PGR (0.38) | CRBNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | claimed |
| WO-2004050624-A1 | SUBSTITUTED 1H-PYRIDINE-2-ONE DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 2004-06-17 | — | — | WO | disclosed |