Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2207325 | 0.92 | L3MBTL1 (0.48) | TDP1L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL8342328 | 0.88 | TDP1 (0.44) | TDP1L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL6067595 | 0.86 | L3MBTL1 (0.47) | TDP1L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL7074449 | 0.85 | MAPT (0.49) | TDP1L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL7224713 | 0.85 | MAPT (0.49) | TDP1L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL9453302 | 0.85 | MAPT (0.49) | TDP1L3MBTL1MAPK1MEN1KMT2A | |
| Malonic Acid SCHEMBL6827744 | 0.81 | MAPT (0.41) | TDP1MAPK1MAPTABCC4ALDH1A1 | |
| SCHEMBL2203256 | 0.81 | L3MBTL1 (0.43) | TDP1L3MBTL1MAPK1MEN1KMT2A | |
| SCHEMBL27163198 | 0.79 | ALDH1A1 (0.48) | MEN1KMT2AMAPTABCC4ALDH1A1 | |
| SCHEMBL8342772 | 0.78 | TDP1 (0.39) | TDP1L3MBTL1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004076425-A1 | IMPROVED SYNTHESIS OF MACROCYCLIC TETRAAMIDO COMPOUNDS AND NEW METAL INSERTION PROCESS | CARNEGIE MELLON UNIVERSITY (US) | 2004-09-10 | — | — | WO | disclosed |