Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074449 | 1.00 | MAPT (0.49) | MAPTALDH1A1USP2SMN1; SMN2CYP3A4 | |
| SCHEMBL9453302 | 1.00 | MAPT (0.49) | MAPTALDH1A1USP2SMN1; SMN2CYP3A4 | |
| SCHEMBL6067595 | 0.98 | L3MBTL1 (0.47) | MAPTALDH1A1USP2SMN1; SMN2CYP3A4 | |
| SCHEMBL2207325 | 0.93 | L3MBTL1 (0.48) | MAPTALDH1A1USP2SMN1; SMN2CYP3A4 | |
| SCHEMBL15445274 | 0.90 | ALDH1A1 (0.47) | MAPTALDH1A1USP2SMN1; SMN2CYP3A4 | |
| SCHEMBL8342328 | 0.86 | TDP1 (0.44) | MAPTALDH1A1USP2SMN1; SMN2CYP3A4 | |
| SCHEMBL2203256 | 0.85 | L3MBTL1 (0.43) | MAPTALDH1A1USP2SMN1; SMN2CYP3A4 | |
| Malonic Acid SCHEMBL6827749 | 0.85 | TDP1 (0.44) | MAPTALDH1A1USP2SMN1; SMN2CYP3A4 | |
| SCHEMBL21073906 | 0.84 | TDP1 (0.55) | MAPTALDH1A1L3MBTL1MAPK1LMNA | |
| SCHEMBL6901399 | 0.84 | TDP1 (0.55) | MAPTALDH1A1L3MBTL1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552068-B1 | Having anti-estrogenic activity; for use in therapy | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-04-22 | — | — | US | disclosed |
| US-6552069-B1 | Having anti-estrogenic activity; for use in therapy | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-1241167-A1 | 3-ETHYL-, 3-PROPYL- OR 3-BUTYL-CHROMAN AND -THIOCHROMAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-09-18 | — | — | EP | disclosed |
| EP-1241166-A1 | 3-METHYL-CHROMAN AND -THIOCHROMAN DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-5247031-A | Olefin polymerization catalyst component, process for production thereof, olefin polymerization catalyst, and process for polymerizing olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-21 | — | — | US | disclosed |