SCHEMBL6827756

SCHEMBL6827756

CC(C)(CNC(=O)Nc1cccc([N+](=O)[O-])c1)CC(=O)N(CC(=O)NO)CC1CCCC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.46
RAB9A P51151 2/20 0.46
MEN1 O00255 10/20 0.43
KMT2A Q03164 10/20 0.43
MAPT P10636 5/20 0.43
HTT P42858 4/20 0.43
POLB P06746 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 4/20 0.42
GAA P10253 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
DDX3X O00571 2/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP8 P22894 1/20 0.42
MMP13 P45452 1/20 0.42
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6825204 0.90 MMP1 (0.44) MEN1KMT2AHTTPOLBALDH1A1
SCHEMBL6825042 0.87 MEN1 (0.43) NPC1RAB9AMEN1KMT2APOLB
SCHEMBL6827891 0.86 NPC1 (0.44) NPC1RAB9AMEN1KMT2APOLB
SCHEMBL6825283 0.86 KMT2A (0.42) NPC1RAB9AMEN1KMT2ASMN1; SMN2
SCHEMBL6827780 0.86 EPHX2 (0.53) NPC1RAB9AMEN1KMT2AHTT
SCHEMBL6822406 0.84 KMT2A (0.49) KMT2AL3MBTL1
SCHEMBL6826087 0.83 KMT2A (0.39) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL6822147 0.82 SMN1; SMN2 (0.41) NPC1RAB9AMEN1KMT2APOLB
SCHEMBL6827533 0.81 RAB9A (0.46) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL6822393 0.81 SLC6A9 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004087643-A1 DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME PROMEDITECH INC. (KR) 2004-10-14 WO claimed