Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 14/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2243379 | 0.90 | HTR2A (0.63) | HTR2AHTR6SCN9A | |
| Hydrochloric Acid SCHEMBL28126599 | 0.89 | HTR2A (0.61) | HTR2AHTR6SCN9A | |
| SCHEMBL25345505 | 0.81 | HTR2A (0.55) | HTR2AHTR6SCN9AMEN1KMT2A | |
| SCHEMBL29078650 | 0.80 | ICMT (0.54) | KDM4E | |
| SCHEMBL9705537 | 0.78 | MTNR1A (0.52) | MEN1KMT2A | |
| SCHEMBL3865396 | 0.77 | HTR2A (0.51) | HTR2AHTR6SCN9A | |
| SCHEMBL9699480 | 0.77 | HTR2A (0.54) | HTR2AHTR6SCN9AHDAC10HDAC6 | |
| SCHEMBL5146534 | 0.76 | MEN1 (0.48) | KDM4EMEN1KMT2ATP53 | |
| SCHEMBL10717308 | 0.76 | KDM4E (0.42) | KDM4EHPGDHSD17B10HDAC10HDAC6 | |
| SCHEMBL20855303 | 0.76 | GPR84 (0.43) | HTR2ASCN9AKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004075847-A2 | METHODS AND COMPOUNDS FOR THE TREATMENT OF Aß ASSOCIATED DISEASES, DISORDERS, AND CONDITIONS | MESSAGE PHARMACEUTICALS, INC. (US) | 2004-09-10 | — | — | WO | disclosed |