Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 16/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675381 | 0.86 | HTR6 (0.55) | HTR2AHTR6SCN9A | |
| SCHEMBL6828081 | 0.84 | HTR6 (0.41) | HTR6HDAC10HDAC6 | |
| SCHEMBL6450630 | 0.83 | MTNR1A (0.50) | — | |
| SCHEMBL12368655 | 0.79 | MAPT (0.62) | SCN9A | |
| Methyl Carbamate SCHEMBL6828082 | 0.77 | HTR2A (0.52) | HTR2AHTR6SCN9AHDAC10HDAC6 | |
| SCHEMBL7528710 | 0.74 | HTR2A (0.59) | HTR2AHTR6SCN9A | |
| SCHEMBL29424269 | 0.74 | HTR2A (0.59) | HTR2AHTR6SCN9A | |
| SCHEMBL25345505 | 0.73 | HTR2A (0.55) | HTR2AHTR6SCN9A | |
| SCHEMBL2243379 | 0.73 | HTR2A (0.63) | HTR2AHTR6SCN9A | |
| SCHEMBL27721427 | 0.73 | HTR2A (0.58) | HTR2AHTR6SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006980-A1 | COMPOUNDS HAVING N-METHYLTRYPTAMINE TRICYCLIC STRUCTURE FOR THE THERAPY OF DEGENERATIVE ENCEPHALOPATHIES | DEPHA TEAM S.R.L. (IT) | 1992-04-30 | — | — | WO | disclosed |