Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683669 | 0.91 | MAPK1 (0.45) | MAPTMAPK1HTR2AADORA2BGLA | |
| SCHEMBL683707 | 0.89 | ADORA2B (0.45) | MAPTMAPK1HTR2AMEN1KMT2A | |
| SCHEMBL684026 | 0.85 | MAPK1 (0.49) | MAPTMAPK1HTR2AMEN1KMT2A | |
| SCHEMBL684045 | 0.84 | MAPT (0.50) | MAPTMAPK1MEN1KMT2AADORA2B | |
| Hydrochloric Acid SCHEMBL11153642 | 0.78 | HTR7 (0.61) | MAPTMAPK1ADORA2B | |
| SCHEMBL683664 | 0.75 | MAPK1 (0.56) | MAPTMAPK1GAAADORA2BGLA | |
| SCHEMBL684023 | 0.75 | HTR2A (0.58) | MAPK1HTR2AKMT2AADORA2BGLA | |
| SCHEMBL683652 | 0.75 | MAPK1 (0.55) | MAPTMAPK1HTR2AGAATP53 | |
| SCHEMBL682830 | 0.74 | ADORA2B (0.50) | HTR2AADORA2BGLABLM | |
| SCHEMBL682822 | 0.74 | RXFP1 (0.57) | MAPTMAPK1ADORA2BTP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | MAPT 1368/4885MAPK1 470/4885HTR2A 1201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.