Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.31 |
| ▸ | SQLE | Q14534 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20875727 | 0.84 | ALDH1A1 (0.32) | ALDH1A1ALOX15 | |
| SCHEMBL8059072 | 0.83 | KMT2A (0.57) | KMT2AMAPTALDH1A1ALOX15MEN1 | |
| SCHEMBL8059069 | 0.83 | KMT2A (0.57) | KMT2AMAPTALDH1A1ALOX15MEN1 | |
| SCHEMBL19480634 | 0.81 | KDM1A (0.37) | KMT2AKDM1AALOX15FNTAFNTB | |
| SCHEMBL424212 | 0.81 | KMT2A (0.34) | KMT2AKDM1AMAPTALDH1A1ALOX15 | |
| SCHEMBL2003932 | 0.79 | KDM1A (0.44) | KMT2AKDM1AMAPTALDH1A1ALOX15 | |
| SCHEMBL2003931 | 0.79 | KDM1A (0.44) | KMT2AKDM1AMAPTALDH1A1ALOX15 | |
| SCHEMBL1658548 | 0.78 | KMT2A (0.38) | KMT2AKDM1AMAPTALDH1A1ALOX15 | |
| SCHEMBL1658549 | 0.78 | KMT2A (0.38) | KMT2AKDM1AMAPTALDH1A1ALOX15 | |
| SCHEMBL5247598 | 0.77 | ALOX15 (0.50) | KMT2AALDH1A1ALOX15MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023938-A1 | Sulfonamide derivatives | TABUCHI TAKANORI (JP) | 2004-02-05 | — | — | US | disclosed |
| US-6586617-B1 | Nontoxic microbiocides such as 4'-chloro-N-ethyl-2'-nitro-p-toluenesulfonanilide, for agricultural or horticultural, prepared by alkylation or nitration | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1174028-A1 | SULFONAMIDE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023938-A1 | Sulfonamide derivatives | FPR1, MRM1, SULT1E1 | KMT2A 563/4885KDM1A 383/4885MAPT 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.