Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.57 |
| ▸ | CTSD | P07339 | 2/20 | 0.52 |
| ▸ | PGA5 | P0DJD9 | 2/20 | 0.52 |
| ▸ | CTSE | P14091 | 2/20 | 0.52 |
| ▸ | PGC | P20142 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331287 | 0.82 | REN (0.63) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL6828559 | 0.79 | CAPN1 (0.40) | — | |
| SCHEMBL7385524 | 0.76 | MEN1 (0.61) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7317104 | 0.76 | MEN1 (0.61) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7345907 | 0.76 | REN (0.51) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7345901 | 0.76 | REN (0.51) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL6828393 | 0.76 | CAPN1 (0.63) | — | |
| SCHEMBL6825437 | 0.75 | REN (0.64) | REN | |
| SCHEMBL7336138 | 0.72 | REN (0.51) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL7331751 | 0.71 | REN (0.54) | RENCTSDPGA5CTSEPGC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1389624-A1 | Phosphorous-containing cysteine and serine protease inhibitors | CEPHALON, INC. (US) | 2004-02-18 | — | — | EP | disclosed |
| EP-0871454-B1 | PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON INC (US) | 2003-11-12 | — | — | EP | disclosed |
| EP-0871454-A4 | — | — | 1998-11-25 | — | — | EP | disclosed |
| EP-0871454-A1 | PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5639732-A | FOR TREATING NERVOUS SYSTEM DISORDERS OR AS ANTIINFLAMMATORY AGENT | CEPHALON, INC. (US) | 1997-06-17 | — | — | US | disclosed |
| WO-1997003679-A1 | PHOSPHOROUS-CONTAINING CYSTEINE AND SERINE PROTEASE INHIBITORS | CEPHALON, INC. (US) | 1997-02-06 | — | — | WO | disclosed |