Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 15/20 | 0.51 |
| ▸ | YAP1 | P46937 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.47 |
| ▸ | CTSE | P14091 | 1/20 | 0.47 |
| ▸ | PGC | P20142 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345901 | 1.00 | REN (0.51) | RENYAP1CTSDPGA5CTSE | |
| SCHEMBL7337967 | 0.92 | YAP1 (0.51) | RENYAP1CACNA1BIL1RNERAP2 | |
| SCHEMBL7337971 | 0.92 | YAP1 (0.51) | RENYAP1CACNA1BIL1RNERAP2 | |
| SCHEMBL7341444 | 0.92 | YAP1 (0.51) | RENYAP1CACNA1BIL1RNERAP2 | |
| SCHEMBL7341442 | 0.92 | YAP1 (0.51) | RENYAP1CACNA1BIL1RNERAP2 | |
| SCHEMBL7339983 | 0.87 | CTSS (0.59) | RENYAP1CACNA1BIL1RNERAP2 | |
| SCHEMBL7345840 | 0.85 | IL1RN (0.53) | RENYAP1IL1RNERAP2ERAP1 | |
| SCHEMBL7371480 | 0.83 | YAP1 (0.53) | RENYAP1CACNA1BIL1RNERAP2 | |
| SCHEMBL7371474 | 0.83 | YAP1 (0.53) | RENYAP1CACNA1BIL1RNERAP2 | |
| SCHEMBL7336248 | 0.82 | BCL2 (0.51) | RENYAP1IL1RNERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | claimed |
| US-6423689-B1 | Peptidyl calcium channel blockers | WARNER-LAMBERT COMPANY | 2002-07-23 | — | — | US | disclosed |