Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.44 |
| ▸ | CNR2 | P34972 | 14/20 | 0.44 |
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6826195 | 0.89 | ESR1 (0.52) | CNR1CNR2ESR1ARESR2 | |
| SCHEMBL6828563 | 0.83 | CNR1 (0.41) | CNR1CNR2ESR1ARESR2 | |
| SCHEMBL5890023 | 0.80 | ALDH1A1 (0.47) | CNR1CNR2 | |
| SCHEMBL6823447 | 0.78 | SHBG (0.52) | ESR1ARESR2 | |
| SCHEMBL6828614 | 0.77 | ALDH1A1 (0.47) | CNR1CNR2 | |
| SCHEMBL6828554 | 0.76 | CNR1 (0.39) | CNR1CNR2AR | |
| SCHEMBL9858398 | 0.75 | TSHR (0.43) | CNR2 | |
| SCHEMBL4401972 | 0.75 | ESR1 (0.52) | CNR1CNR2ESR1ARESR2 | |
| SCHEMBL13096081 | 0.74 | SHBG (0.57) | CNR1CNR2ESR1ARESR2 | |
| SCHEMBL9858653 | 0.73 | TSHR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040230073-A1 | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | AJINOMOTO CO., INC. (JP) | 2004-11-18 | — | — | US | disclosed |
| US-20020132032-A1 | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | AJINOMOTO CO., INC. (JP) | 2002-09-19 | — | — | US | disclosed |
| EP-1219633-A1 | PROCESS FOR PRODUCING ASPARTAME DERIVATIVE, CRYSTALS THEREOF, NOVEL PRODUCTION INTERMEDIATES THEREFOR AND PROCESS FOR PRODUCING THE INTERMEDIATE | Ajinomoto Co., Inc. (JP) | 2002-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040230073-A1 | Process for production of aspartame derivative, crystal thereof, novel production intermediate therefor, and process for production of intermediate thereof | IAPP, DPP4, SI | CNR1 4741/4885CNR2 4776/4885ESR1 4733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.