Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2754136 | 0.84 | SLC6A2 (0.38) | MLYCDALOX5SLC6A2SLC6A4NR1H3 | |
| SCHEMBL1818385 | 0.75 | ALDH1A1 (0.46) | ALOX5SLC6A2SLC6A4ALDH1A1GLA | |
| SCHEMBL8586520 | 0.73 | ALOX5 (0.43) | ALOX5SLC6A2SLC6A4ALDH1A1GLA | |
| SCHEMBL1821413 | 0.73 | ALOX5 (0.43) | ALOX5SLC6A2SLC6A4ALDH1A1GLA | |
| SCHEMBL11760439 | 0.72 | SLC6A2 (0.45) | ALOX5SLC6A2SLC6A4ALDH1A1GLA | |
| Carbamic Acid SCHEMBL27977071 | 0.71 | ALDH1A1 (0.46) | MLYCDALOX5SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL31467993 | 0.70 | SLC6A2 (0.44) | ALOX5SLC6A2SLC6A4ALDH1A1GLA | |
| SCHEMBL6828243 | 0.69 | AR (0.35) | MLYCDSLC6A2SLC6A4TP53CYP2D6 | |
| SCHEMBL1821353 | 0.68 | SLC6A2 (0.45) | ALOX5SLC6A2SLC6A4ALDH1A1GLA | |
| SCHEMBL2754132 | 0.68 | NR1H2 (0.45) | NR1H3ALDH1A1GLATSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425270-A2 | METHODS AND INTERMEDIATES FOR PREPARING 4-AMINOQUINOLINE CETP INHIBITORS | Pfizer Products Inc. (US) | 2004-06-09 | — | — | EP | disclosed |
| WO-2002088085-A2 | METHODS AND INTERMEDIATES FOR PREPARING 4-AMINOQUINOLINE CETP INHIBITORS | PFIZER PRODUCTS INC. (US) | 2002-11-07 | — | — | WO | disclosed |